A decrease in the expression of the pro-ferroptotic proteins ACSL4, TFR1, and VDAC2/3 and a decrease in dihydroethidium (DHE) fluorescence, iron, malondialdehyde (MDA), and myeloperoxidase (MPO) were further observed in metformin-treated mice
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Studies have shown that interferon-induced transmembrane protein (IFITM) is positively associated with gastric cancer progression, recurrence and mortality (23,24)